Modafinil

January 12, 2011

Modafinil is used to counter excessive sleepiness due to narcolepsy.

It stimulates the central nervous system and shares some similarities with amphetamine. It is considered a mild stimulant and is, unlike amphetamine, not associated with euphoric effects at high doses. The risk of development of drug dependence or tolerance of this drug is low, at least in patients without prior history of drug dependence. Modafinil has been classified as a performance enhancing stimulant by WADA since 2004. While several mainstream sleep experts say they doubt the drug has performance enhancing effects, a study from 2004 showed that Modafinil prolongs exercise time to exhaustion while performing at 85 % of VO2max and also reduces the perception of effort required to maintain the threshold (1). Jacobs, I; Bell, DG (2004) \\\"Effects of acute modafinil ingestion on exercise time to exhaustion\\\" Med Sci Sports Exerc 36(6):1078-1082 1. http://en.wikipedia.org/ http://www.fass.se/ Written by International Doping Tests & Management (www.idtm.se) for IADB

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